Siete in: Attività di Ricerca / Pubblicazioni Dipartimento / Benedetti Pietro

BENEDETTI PIETRO: PUBBLICAZIONI

1 Mattoccia E, Baldi MI, Carrara G, Fruscoloni P, Benedetti P, Tocchini-valentini GP.
Separation of RNA transcription and processing activities from X. laevis germinal vesicles.
CELL. Nov 1979; 18(3): 643-8
2 Baldi MI, Benedetti P, Mattoccia E, Tocchini-valentini GP.
In vitro catenation and decatenation of DNA and a novel eucaryotic ATP-dependent topoisomerase.
CELL. Jun 1980; 20(2): 461-7
3 Benedetti P, Baldi MI, Mattoccia E, Tocchini-valentini GP.
Purification and characterization of Xenopus laevis topoisomerase II.
EMBO J. 1983; 2(8): 1303-8
4 Fabrizio P, Coppo A, Fruscoloni P, Benedetti P, Di Segni G, Tocchini-valentini GP.
Comparative mutational analysis of wild-type and stretched tRNA3(Leu) gene promoters.
P NATL ACAD SCI USA. Dec 1987; 84(24): 8763-7
5 Bjornsti MA, Benedetti P, Viglianti GA, Wang JC.
Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumor drug camptothecin.
CANCER RES. Nov 1989; 49(22): 6318-23
6 Ostrander EA, Benedetti P, Wang JC.
Template supercoiling by a chimera of yeast GAL4 protein and phage T7 RNA polymerase.
SCIENCE. Sep 1990; 249(4974): 1261-5
7 Benedetti P, Fiorani P, Capuani L, Wang JC.
Camptothecin resistance from a single mutation changing glycine 363 of human DNA topoisomerase I to cysteine.
CANCER RES. Sep 1993; 53(18): 4343-8
8 Vassetzky YS, Dang Q, Benedetti P, Gasser SM.
Topoisomerase II forms multimers in vitro: effects of metals, beta-glycerophosphate, and phosphorylation of its C-terminal domain.
MOL CELL BIOL. Oct 1994; 14(10): 6962-74
9 Hanai R, Liu R, Benedetti P, Caron PR, Lynch AS, Wang JC.
Molecular dissection of a protein SopB essential for Escherichia coli F plasmid partition.
J BIOL CHEM. Jul 1996; 271(29): 17469-75
10 Benedetti P, Silvestri A, Fiorani P, Wang JC.
Study of yeast DNA topoisomerase II and its truncation derivatives by transmission electron microscopy.
J BIOL CHEM. May 1997; 272(18): 12132-7
11 Reid RJ, Benedetti P, Bjornsti MA.
Yeast as a model organism for studying the actions of DNA topoisomerase-targeted drugs.
BIOCHIM BIOPHYS ACTA. Oct 1998; 1400(1-3): 289-300
12 Hann C, Evans DL, Fertala J, Benedetti P, Bjornsti MA, Hall DJ.
Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I.
J BIOL CHEM. Apr 1998; 273(14): 8425-33
13 Benedetti P, Benchokroun Y, Houghton P.
Analysis of Camptothecin resistance in yeast: relevance to cancer therapy.
DRUG RESIST UPDATE. APR 1998; 1: 176-183
14 Benedetti P, Benchokroun Y, Houghton PJ, Bjornsti MA.
Analysis of comptothecin resistance in yeast: relevance to cancer therapy.
DRUG RESIST UPDATE. Jun 1998; 1(3): 176-83
15 Fiorani P, Amatruda JF, Silvestri A, Butler RH, Bjornsti MA, Benedetti P.
Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity.
MOL PHARMACOL. Dec 1999; 56(6): 1105-15
16 Fiorentino L, Pertica C, Fiorini M, Talora C, Crescenzi M, Castellani L, Alem S, Benedetti P, Segatto O.
Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain.
MOL CELL BIOL. Oct 2000; 20(20): 7735-50
17 Chillemi G, Fiorani P, Benedetti P, Desideri A.
Protein concerted motions in the DNA-human topoisomerase I complex.
NUCLEIC ACIDS RES. Mar 2003; 31(5): 1525-35
18 Fiorani P, Bruselles A, Falconi M, Chillemi G, Desideri A, Benedetti P.
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.
J BIOL CHEM. Aug 2003
19 Woo MH, Losasso C, Guo H, Pattarello L, Benedetti P, Bjornsti MA.
Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality.
P NATL ACAD SCI USA. Oct 2003
20 Chillemi G, Fiorani P, Benedetti P, Desideri A.
Protein concerted motions in the DNA-human topoisomerase I complex.
NUCLEIC ACIDS RES. Mar 2003; 31(5): 1525-35
21 Fiorani P, Bruselles A, Falconi M, Chillemi G, Desideri A, Benedetti P.
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.
J BIOL CHEM. Aug 2003
22 Fiorani P, Reid RJ, Schepis A, Jacquiau HR, Guo H, Thimmaiah P, Benedetti P, Bjornsti MA.
The deubiquitinating enzyme Doa4p protects cells from DNA topoisomerase I poisons.
J BIOL CHEM. Feb 2004
23 Chillemi G, Fiorani P, Castelli S, Bruselles A, Benedetti P, Desideri A.
Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study.
NUCLEIC ACIDS RES. 2005; 33(10): 3339-50
24 Losasso C, Cretaio E, Palle K, Pattarello L, Bjornsti MA, Benedetti P.
Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality.
J BIOL CHEM. Feb 2007
25 Corbett KD, Benedetti P, Berger JM.
Holoenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VI.
NAT STRUCT MOL BIOL. Jul 2007
26 Cretaio E, Pattarello L, Fontebasso Y, Benedetti P, Losasso C.
Human DNA topoisomerase IB: structure and functions.
ITAL J BIOCHEM. Jun 2007; 56(2): 91-102
27 Palle K, Pattarello L, Van Der Merwe M, Losasso C, Benedetti P, Bjornsti MA.
Disulfide crosslinks reveal conserved features of dna topoisomerase I architecture and a role for the N-terminus in clamp closure.
J BIOL CHEM. Aug 2008
28 Chillemi G, D'annessa I, Fiorani P, Losasso C, Benedetti P, Desideri A.
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations.
NUCLEIC ACIDS RES. Sep 2008
29 Losasso C, Cretaio E, Fiorani P, D'annessa I, Chillemi G, Benedetti P.
A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance.
NUCLEIC ACIDS RES. Sep 2008
30 Chillemi G, D'annessa I, Fiorani P, Losasso C, Benedetti P, Desideri A.
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations.
NUCLEIC ACIDS RES. Oct 2008; 36(17): 5645-51
31 Vezzù K, Sforza E, Sudiro M, Benedetti P, Losasso C, Bertucco A.
Production of bioethanol under high pressure of CO2: The effect of process conditions.
The Journal of Supercritical Fluids. 2009; 220-227