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DE BERNARD MARINA: PUBBLICAZIONI

1 Papini E, De Bernard M, Bugnoli M, Milia E, Rappuoli R, Montecucco C.
Cell vacuolization induced by Helicobacter pylori: inhibition by bafilomycins A1, B1, C1 and D.
FEMS MICROBIOL LETT. Oct 1993; 113(2): 155-9
2 Papini E, Bugnoli M, De Bernard M, Figura N, Rappuoli R, Montecucco C.
Bafilomycin A1 inhibits Helicobacter pylori-induced vacuolization of HeLa cells.
MOL MICROBIOL. Jan 1993; 7(2): 323-7
3 Papini E, De Bernard M, Milia E, Bugnoli M, Zerial M, Rappuoli R, Montecucco C.
Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments.
P NATL ACAD SCI USA. Oct 1994; 91(21): 9720-4
4 Manetti R, Massari P, Burroni D, De Bernard M, Marchini A, Olivieri R, Papini E, Montecucco C, Rappuoli R, Telford JL.
Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies.
INFECT IMMUN. Nov 1995; 63(11): 4476-80
5 De Bernard M, Papini E, De Filippis V, Gottardi E, Telford J, Manetti R, Fontana A, Rappuoli R, Montecucco C.
Low pH activates the vacuolating toxin of Helicobacter pylori, which becomes acid and pepsin resistant.
J BIOL CHEM. Oct 1995; 270(41): 23937-40
6 Papini E, Gottardi E, Satin B, De Bernard M, Massari P, Telford J, Rappuoli R, Sato SB, Montecucco C.
The vacuolar ATPase proton pump is present on intracellular vacuoles induced by Helicobacter pylori.
J MED MICROBIOL. Aug 1996; 45(2): 84-9
7 De Bernard M, Arico B, Papini E, Rizzuto R, Grandi G, Rappuoli R, Montecucco C.
Helicobacter pylori toxin VacA induces vacuole formation by acting in the cell cytosol.
MOL MICROBIOL. Nov 1997; 26(4): 665-74
8 Papini E, Satin B, Bucci C, De Bernard M, Telford JL, Manetti R, Rappuoli R, Zerial M, Montecucco C.
The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin.
EMBO J. Jan 1997; 16(1): 15-24
9 De Bernard M, Burroni D, Papini E, Rappuoli R, Telford J, Montecucco C.
Identification of the Helicobacter pylori VacA toxin domain active in the cell cytosol.
INFECT IMMUN. Dec 1998; 66(12): 6014-6
10 De Bernard M, Moschioni M, Papini E, Telford J, Rappuoli R, Montecucco C.
Cell vacuolization induced by Helicobacter pylori VacA toxin: cell line sensitivity and quantitative estimation.
TOXICOL LETT. Oct 1998; 99(2): 109-15
11 De Bernard M, Moschioni M, Papini E, Telford JL, Rappuoli R, Montecucco C.
TPA and butyrate increase cell sensitivity to the vacuolating toxin of Helicobacter pylori.
FEBS LETT. Oct 1998; 436(2): 218-22
12 Papini E, Satin B, De Bernard M, Molinari M, Aricò B, Galli C, Telford JR, Rappuoli R, Montecucco C.
Action site and cellular effects of cytotoxin VacA produced by Helicobacter pylori.
FOLIA MICROBIOL. 1998; 43(3): 279-84
13 Papini E, Satin B, Norais N, De Bernard M, Telford JL, Rappuoli R, Montecucco C.
Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin.
J CLIN INVEST. Aug 1998; 102(4): 813-20
14 Molinari M, Galli C, De Bernard M, Norais N, Ruysschaert JM, Rappuoli R, Montecucco C.
The acid activation of Helicobacter pylori toxin VacA: structural and membrane binding studies.
BIOCHEM BIOPH RES CO. Jul 1998; 248(2): 334-40
15 Reyrat JM, Charrel M, Pagliaccia C, Burroni D, Lupetti P, De Bernard M, Ji X, Norais N, Papini E, Dallai R, Rappuoli R, Telford JL.
Characterisation of a monoclonal antibody and its use to purify the cytotoxin of Helicobacter pylori.
FEMS MICROBIOL LETT. Aug 1998; 165(1): 79-84
16 Pagliaccia C, De Bernard M, Lupetti P, Ji X, Burroni D, Cover TL, Papini E, Rappuoli R, Telford JL, Reyrat JM.
The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity.
P NATL ACAD SCI USA. Aug 1998; 95(17): 10212-7
17 Montecucco C, Papini E, De Bernard M, Zoratti M.
Molecular and cellular activities of Helicobacter pylori pathogenic factors.
FEBS LETT. Jun 1999; 452(1-2): 16-21
18 Tombola F, Carlesso C, Szabò I, De Bernard M, Reyrat JM, Telford JL, Rappuoli R, Montecucco C, Papini E, Zoratti M.
Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: possible implications for the mechanism of cellular vacuolation.
BIOPHYS J. Mar 1999; 76(3): 1401-9
19 Reyrat JM, Lanzavecchia S, Lupetti P, De Bernard M, Pagliaccia C, Pelicic V, Charrel M, Ulivieri C, Norais N, Ji X, Cabiaux V, Papini E, Rappuoli R, Telford JL.
3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin.
J MOL BIOL. Jul 1999; 290(2): 459-70
20 Rossetto O, De Bernard M, Pellizzari R, Vitale G, Caccin P, Schiavo G, Montecucco C.
Bacterial toxins with intracellular protease activity.
CLIN CHIM ACTA. Feb 2000; 291(2): 189-99
21 De Bernard M, Moschioni M, Napolitani G, Rappuoli R, Montecucco C.
The VacA toxin of Helicobacter pylori identifies a new intermediate filament-interacting protein.
EMBO J. Jan 2000; 19(1): 48-56
22 Montecucco C, De Bernard M, Papini E, Zoratti M.
Helicobacter pylori vacuolating cytotoxin: cell intoxication and anion-specific channel activity.
CURR TOP MICROBIOL. 2001; 257: 113-29
23 Dundon WG, De Bernard M, Montecucco C.
Virulence factors of Helicobacter pylori.
INT J MED MICROBIOL. Mar 2001; 290(8): 647-58
24 Moschioni M, Tombola F, De Bernard M, Coelho A, Zitzer A, Zoratti M, Montecucco C.
The Vibrio cholerae haemolysin anion channel is required for cell vacuolation and death.
CELL MICROBIOL. Jul 2002; 4(7): 397-409
25 Montemurro P, Nishioka H, Dundon WG, De Bernard M, Del Giudice G, Rappuoli R, Montecucco C.
The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a potent stimulant of mast cells.
EUR J IMMUNOL. Mar 2002; 32(3): 671-6
26 De Bernard M, Moschioni M, Habermann A, Griffiths G, Montecucco C.
Cell vacuolization induced by Helicobacter pylori VacA cytotoxin does not depend on late endosomal SNAREs.
CELL MICROBIOL. Jan 2002; 4(1): 11-8
27 Runz H, Rietdorf J, Tomic I, De Bernard M, Beyreuther K, Pepperkok R, Hartmann T.
Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.
J NEUROSCI. Mar 2002; 22(5): 1679-89
28 Montecucco C, De Bernard M.
Molecular and cellular mechanisms of action of the vacuolating cytotoxin (VacA) and neutrophil-activating protein (HP-NAP) virulence factors of Helicobacter pylori.
MICROBES INFECT. Jul 2003; 5(8): 715-21
29 Montecucco C, De Bernard M.
Immunosuppressive and Proinflammatory Activities of the VacA Toxin of Helicobacter pylori.
J EXP MED. Dec 2003; 198(12): 1767-71
30 De Bernard M, Cappon A, Del Giudice G, Rappuoli R, Montecucco C.
The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori.
INT J MED MICROBIOL. Apr 2004; 293(7-8): 589-97
31 De Bernard M, Cappon A, Pancotto L, Ruggiero P, Rivera J, Del Giudice G, Montecucco C.
The Helicobacter pylori VacA cytotoxin activates RBL-2H3 cells by inducing cytosolic calcium oscillations.
CELL MICROBIOL. Feb 2005; 7(2): 191-198
32 Spirl C, Fiorotto R, Song L, Santos-sacchi J, Okolicsanyi L, Masier S, Rocchi L, Pia Vairetti M, De Bernard M, Melero S, Pozzan T, Strazzabosco M.
Glibenclamide stimulates fluid secretion in rodent cholangiocytes through a cystic fibrosis transmembrane conductance regulator-independent mechanism.
GASTROENTEROLOGY. Jul 2005; 129(1): 220-33
33 Genisset C, Galeotti CL, Lupetti P, Mercati D, Skibinski DA, Barone S, Battistutta R, De Bernard M, Telford JL.
A Helicobacter pylori Vacuolating Toxin Mutant That Fails To Oligomerize Has a Dominant Negative Phenotype.
INFECT IMMUN. Mar 2006; 74(3): 1786-94
34 Amedei A, Cappon A, Codolo G, Cabrelle A, Polenghi A, Benagiano M, Tasca E, Azzurri A, D'elios MM, Del Prete G, De Bernard M.
The neutrophil-activating protein of Helicobacter pylori promotes Th1 immune responses.
J CLIN INVEST. Mar 2006
35 Polenghi A, Bossi F, Fischetti F, Durigutto P, Cabrelle A, Tamassia N, Cassatella MA, Montecucco C, Tedesco F, De Bernard M.
The Neutrophil-Activating Protein of Helicobacter pylori Crosses Endothelia to Promote Neutrophil Adhesion In Vivo.
J IMMUNOL. Feb 2007; 178(3): 1312-20
36 Genisset C, Puhar A, Calore F, De Bernard M, Dell'antone P, Montecucco C.
The concerted action of the Helicobacter pylori cytotoxin VacA and of the v-ATPase proton pump induces swelling of isolated endosomes.
CELL MICROBIOL. Jan 2007
37 D'elios MM, Montecucco C, De Bernard M.
VacA and HP-NAP, Ying and Yang of Helicobacter pylori-associated gastric inflammation.
CLIN CHIM ACTA. Feb 2007
38 D'elios MM, Amedei A, Cappon A, Del Prete G, De Bernard M.
The neutrophil-activating protein of Helicobacter pylori (HP-NAP) as an immune modulating agent.
FEMS IMMUNOL MED MIC. May 2007
39 Mazzon C, Baldani-guerra B, Cecchini P, Kasic T, Viola A, De Bernard M, Aric B, Gerosa F, Papini E.
IFN-{gamma} and R-848 Dependent Activation of Human Monocyte-Derived Dendritic Cells by Neisseria meningitidis Adhesin A.
J IMMUNOL. Sep 2007; 179(6): 3904-16
40 Arcidiacono D, Odom S, Frossi B, Rivera J, Paccani SR, Baldari CT, Pucillo C, Montecucco C, De Bernard M.
The Vibrio cholerae cytolysin (VCC) promotes activation of mast cell (T helper 2) cytokine production.
CELL MICROBIOL. Nov 2007
41 Farinati F, Cardin R, Bortolami M, Nitti D, Basso D, De Bernard M, Cassaro M, Sergio A, Rugge M.
Oxidative DNA damage in gastric cancer: CagA status and OGG1 gene polymorphism.
INT J CANCER. Mar 2008
42 Codolo G, Mazzi P, Amedei A, Del Prete G, Berton G, D'elios MM, De Bernard M.
The Neutrophil Activating Protein of Helicobacter pylori down-modulates Th2 inflammation in OVA-induced allergic asthma.
CELL MICROBIOL. Jul 2008
43 Farinati F, Cardin R, Bortolami M, Nitti D, Basso D, De Bernard M, Cassaro M, Sergio A, Rugge M.
Oxidative DNA damage in gastric cancer: CagA status and OGG1 gene polymorphism.
INT J CANCER. Mar 2008
44 Codolo G, Mazzi P, Amedei A, Del Prete G, Berton G, D'elios MM, De Bernard M.
The Neutrophil Activating Protein of Helicobacter pylori down-modulates Th2 inflammation in OVA-induced allergic asthma.
CELL MICROBIOL. Jul 2008
45 Del Prete G, Chiumiento L, Amedei A, Piazza M, D'elios MM, Codolo G, De Bernard M, Masetti M, Bruschi F.
Immunosuppression of T(H)2 responses in Trichinella spiralis infection by Helicobacter pylori neutrophil-activating protein.
J ALLERGY CLIN IMMUN. Sep 2008
46 Codolo G, Amedei A, Steere AC, Papinutto E, Cappon A, Polenghi A, Benagiano M, Paccani SR, Sambri V, Del Prete G, Baldari CT, Zanotti G, Montecucco C, D'elios MM, De Bernard M.
Borrelia burgdorferi NapA-driven Th17 cell inflammation in lyme arthritis.
ARTH RHEUM/AR C RES. Oct 2008; 58(11): 3609-3617
47 Salata C, Curtarello M, Calistri A, Sartori E, Sette P, De Bernard M, Parolin C, Pal G.
vOX2 glycoprotein of human herpesvirus 8 modulates human primary macrophages activity.
J CELL PHYSIOL. Feb 2009
48 D'elios MM, Codolo G, Amedei A, Mazzi P, Berton G, Zanotti G, Del Prete G, De Bernard M.
Helicobacter pylori, asthma and allergy.
FEMS IMMUNOL MED MIC. Feb 2009
49 Debellis L, Diana A, Arcidiacono D, Fiorotto R, Portincasa P, Altomare DF, Spirlì C, De Bernard M.
The Vibrio cholerae cytolysin promotes chloride secretion from intact human intestinal mucosa.
PLOS ONE. 03 2009; 4: 5074